http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#Head http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#assertion http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#provenance http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#pubinfo http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#assertion http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#_1 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#_2 http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0016301 http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#_2 http://purl.obolibrary.org/obo/RO_0002204 http://www.ncbi.nlm.nih.gov/gene/2475 http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#_3 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#_4 http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0016301 http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#_4 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=11283 http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#_5 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#_3 http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/increases http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#_1 http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#assertion http://www.w3.org/2000/01/rdf-schema#label kin(p(EGID:2475)) -> kin(p(HGNC:SRC)) http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#provenance http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#_7 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#_6 http://www.w3.org/ns/prov#value A natural macrocyclic lactone produced by the bacterium Streptomyces hygroscopicus, with imunosuppressant properties. In cells, sirolimus binds to the immunophilin, FK Binding Protein-12 (FKBP-12) to generate an immunosuppressive complex that binds to and inhibits the activation of the mammalian Target Of Rapamycin (mTOR), a key regulatory kinase http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#_6 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/15251441 http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#_7 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/15251441 http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#_6 http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo#pubinfo http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo http://purl.org/dc/terms/created 2014-07-03T14:30:25.833+02:00 http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAZ6s8FgjR7AdbmCc2j03JSiYa00uOjw31IITH6dJKyQo http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234