. . . . . . . . . . . . . . . . . "gtp(p(PFH:\"RAS Family\")) => cat(p(HGNC:TIAM1))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "Here we demonstrate that Tiam1, a Rac-specific GEF, preferentially associates with activated GTP-bound Ras through a Ras-binding domain. Furthermore, activated Ras and Tiam1 cooperate to cause synergistic formation of Rac-GTP in a PI(3)K-independent manner. Thus, Tiam1 can function as an effector that directly mediates Ras activation of Rac." . . "Selventa" . . . . "2014-07-03T14:30:04.591+02:00"^^ . . .