http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#Head http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80 http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#assertion http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80 http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#provenance http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80 http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#pubinfo http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#assertion http://resource.belframework.org/belframework/1.0/namespace/selventa-named-mouse-complexes/Nfkb%20Complex http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0043234 http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#_1 http://purl.obolibrary.org/obo/RO_0002204 http://www.informatics.jax.org/marker/MGI:98872 http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#_2 http://semanticscience.org/resource/SIO_000139 http://resource.belframework.org/belframework/1.0/namespace/selventa-named-mouse-complexes/Nfkb%20Complex http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0042789 http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#_3 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10090 http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#_2 http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/decreases http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#_1 http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#assertion http://www.w3.org/2000/01/rdf-schema#label p(MGI:Twist1) -| tscript(complex(NCM:"Nfkb Complex")) http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#provenance http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#_5 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#_4 http://www.w3.org/ns/prov#value To further define the mechanism for inhibition of the cytokine promoters by twist, we tested whether twist could inhibit NF-B activity, using a luciferase reporter driven by four canonical B binding sites (4xB-luc). This reporter can be induced by p65 or treatment with TNF. In either case, activation of the reporter was strongly inhibited by twist-2, as well as twist-1 (Figure 6D). These findings suggested that twist inhibits NF-B-dependent transcriptional activation. http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#_4 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/12553906 http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#_5 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/12553906 http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#_4 http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80#pubinfo http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80 http://purl.org/dc/terms/created 2014-07-03T14:30:09.638+02:00 http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80 http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAZNCOWgWxoJHGkHdSpYVwyDm28pNrjprpWh1Z17lpK80 http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234