dgn-np:NP12520.RAZSt4U1_olITu9NvpO2ztcojx--yp-Fw77fDVGquKRHA130_provenance {
  dgn-np:NP12520.RAZSt4U1_olITu9NvpO2ztcojx--yp-Fw77fDVGquKRHA130_assertion dcterms:description "[Significant genes in myeloma plasma cells from patients that were associated with early-onset bortezomib-induced peripheral neuropathy were the enzyme coding genes RHOBTB2 (upregulated by 159 times; p=4510(-5)), involved in drug-induced apoptosis, CPT1C (144 times; p=2910(-7)), involved in mitochondrial dysfunction, and SOX8 (168 times; p=42810(-13)), involved in development of peripheral nervous system.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en ;
    wi:evidence dgn-void:source_evidence_curated ;
    sio:SIO_000772 miriam-pubmed:20864405 ;
    prov:wasDerivedFrom dgn-void:ctd_human-20130708 ;
    prov:wasGeneratedBy eco:ECO_0000218 .
  dgn-void:ctd_human-20130708 pav:importedOn "2013-07-24"^^xsd:date .
  dgn-void:source_evidence_curated a eco:ECO_0000205 ;
    rdfs:comment "Gene-disease associations manually curated."@en ;
    rdfs:label "DisGeNET evidence - CURATED"@en .
}