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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RA_-IdpI5C_4rGZtUU9MRm2JEYDCD2NCvQlSaGOYbC2Hg#_5 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RA_-IdpI5C_4rGZtUU9MRm2JEYDCD2NCvQlSaGOYbC2Hg#_4 http://www.w3.org/ns/prov#value No pretreatment or pretreatment with insulin for 4 hours resulted in similar levels of Bovine growth hormone induced tyrosine phosphorylated STAT5. However following insulin pretreatment for 16, 20, 24 hours, bGH- induced phosphorylated Stat5 was reduced. Moreover Insulin pretreatment for 16 hours also significantly inhibited bGH induced Jak2 tyrosine phosphorylation. These results demonstrate that Growth hormone stimulated Jak2/Stat5 phosphorylation was inhibited by chronic insulin treatment and Jak2 mediates STA5B phosphorylation. http://www.tkuhn.ch/bel2nanopub/RA_-IdpI5C_4rGZtUU9MRm2JEYDCD2NCvQlSaGOYbC2Hg#_4 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/10224108 http://www.tkuhn.ch/bel2nanopub/RA_-IdpI5C_4rGZtUU9MRm2JEYDCD2NCvQlSaGOYbC2Hg#_5 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RA_-IdpI5C_4rGZtUU9MRm2JEYDCD2NCvQlSaGOYbC2Hg#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/10224108 http://www.tkuhn.ch/bel2nanopub/RA_-IdpI5C_4rGZtUU9MRm2JEYDCD2NCvQlSaGOYbC2Hg#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RA_-IdpI5C_4rGZtUU9MRm2JEYDCD2NCvQlSaGOYbC2Hg#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RA_-IdpI5C_4rGZtUU9MRm2JEYDCD2NCvQlSaGOYbC2Hg#_4 http://www.tkuhn.ch/bel2nanopub/RA_-IdpI5C_4rGZtUU9MRm2JEYDCD2NCvQlSaGOYbC2Hg#pubinfo http://www.tkuhn.ch/bel2nanopub/RA_-IdpI5C_4rGZtUU9MRm2JEYDCD2NCvQlSaGOYbC2Hg http://purl.org/dc/terms/created 2014-07-03T14:29:47.003+02:00 http://www.tkuhn.ch/bel2nanopub/RA_-IdpI5C_4rGZtUU9MRm2JEYDCD2NCvQlSaGOYbC2Hg http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RA_-IdpI5C_4rGZtUU9MRm2JEYDCD2NCvQlSaGOYbC2Hg http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234