sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_6 ;
    pav:version "1.4" .
  sub:_5 prov:value "HRG Stimulates Tyrosine Phosphorylation of beta -Catenin through the PI 3-Kinase Pathway and Its Association with HER2-- Because HRG has been shown to activate several signaling pathways (4, 5, 7, 10, 36), we next examined the nature of the signaling pathway responsible for HRG-induced beta -catenin tyrosine phosphorylation. Our results showed that the HRG-increased phosphorylation status of the immunoprecipitated beta -catenin was completely reduced by blocking the PI 3-kinase pathway by pharmacological inhibitor LY294002 (PI3K inhibitor) and only modestly reduced by inhibition of the MAP kinase pathway with the chemical inhibitor PD98059 (MEK1 inhibitor) (Fig. 2A). " ;
    prov:wasQuotedFrom pubmed:11328805 .
  sub:_6 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:11328805 ;
    prov:wasDerivedFrom beldoc: , sub:_5 .
}