http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#Head http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#assertion http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#provenance http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#pubinfo http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#assertion http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#_1 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#_2 http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0016301 http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#_2 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=6840 http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#_3 http://www.selventa.com/vocabulary/variantOf http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=2514 http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:00000 http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:00696 http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#_4 http://purl.obolibrary.org/obo/BFO_0000066 http://www.lgcstandards-atcc.org/Products/All/HTB-22.aspx http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#_4 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#_3 http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/increases http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#_1 http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#assertion http://www.w3.org/2000/01/rdf-schema#label kin(p(HGNC:MAP2K1)) -> p(HGNC:CTNNB1,pmod(P,Y)) http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#provenance http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#_6 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#_5 http://www.w3.org/ns/prov#value HRG Stimulates Tyrosine Phosphorylation of beta -Catenin through the PI 3-Kinase Pathway and Its Association with HER2-- Because HRG has been shown to activate several signaling pathways (4, 5, 7, 10, 36), we next examined the nature of the signaling pathway responsible for HRG-induced beta -catenin tyrosine phosphorylation. Our results showed that the HRG-increased phosphorylation status of the immunoprecipitated beta -catenin was completely reduced by blocking the PI 3-kinase pathway by pharmacological inhibitor LY294002 (PI3K inhibitor) and only modestly reduced by inhibition of the MAP kinase pathway with the chemical inhibitor PD98059 (MEK1 inhibitor) (Fig. 2A). http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#_5 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/11328805 http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#_6 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/11328805 http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#_5 http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc#pubinfo http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc http://purl.org/dc/terms/created 2014-07-03T14:29:55.774+02:00 http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RA_l3FSODXKbd-LJqaED8JbrWa_flLZ6Yd_ih-dgQq_pc http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234