. . . . . . . "[We found that ACS-associated mutations in GNAI3 produce dominant-negative G?(i3) mutant proteins that couple to ET(A)R but cannot bind and hydrolyze guanosine triphosphate, resulting in the prevention of endothelin-mediated activation of G?(q/11) and PLC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:13:02+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .