@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAaVw7JHsDOo_gu3qbHK91s-sCVtL4GgyWvbnfPqqEl4Y> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAaVw7JHsDOo_gu3qbHK91s-sCVtL4GgyWvbnfPqqEl4Y#> .
@prefix beldoc: <http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix hasAgent: <http://semanticscience.org/resource/SIO_000139> .
@prefix proteinModification: <http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:00000> .
@prefix psimod: <http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .
sub:Head {
   this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
   sub:_1 hasAgent: sub:_2 ;
    a go:0016301 .
  sub:_2 geneProductOf: hgnc:10251 ;
    a Protein: .
  sub:_3 belv:variantOf hgnc:7373 ;
    a proteinModification: , psimod:00696 .
  sub:_4 occursIn: species:9606 ;
    rdf:object sub:_3 ;
    rdf:predicate belv:directlyIncreases ;
    rdf:subject sub:_1 ;
    a rdf:Statement .
  sub:assertion rdfs:label "kin(p(HGNC:ROCK1)) => p(HGNC:MSN,pmod(P,T,558))" .
}
sub:provenance {
   beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_6 ;
    pav:version "1.4" .
  sub:_5 prov:value "A second proposal has been that phosphorylation activates binding functions of moesin. In human platelets, for instance, thrombin activation leads to a rapid, but transient, increase in the phosphorylation of a single threonine, Thr558...This residue is conserved in moesin, ezrin, and radixin, and it is modified also in RAW macrophages (34), Swiss3T3 cells (29),1 NIH3T3 cells,2 and RB2H3 mast cells. Phosphorylation at this site is regulated by the activity of Rho, and Rho-associated kinase phosphorylates two residues in the C-terminal region, one of which is Thr558 (29). Thr558 can also be phosphorylated by theta-phosphokinase C (35)." ;
    prov:wasQuotedFrom pubmed:10212266 .
  sub:_6 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:10212266 ;
    prov:wasDerivedFrom beldoc: , sub:_5 .
}
sub:pubinfo {
   this: dct:created "2014-07-03T14:29:46.892+02:00"^^xsd:dateTime ;
    pav:createdBy orcid:0000-0001-6818-334X , orcid:0000-0002-1267-0234 .
}