@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAalddCVBDAkgDNKl55i-9Gj_GLsuATYTkiQ9DlK6i54o> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAalddCVBDAkgDNKl55i-9Gj_GLsuATYTkiQ9DlK6i54o#> .
@prefix beldoc: <http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix atcc: <http://www.lgcstandards-atcc.org/Products/All/> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix mesh: <http://purl.bioontology.org/ontology/MSH/> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  sub:_1 geneProductOf: hgnc:7997;
    a Protein: .
  
  sub:_2 geneProductOf: hgnc:2514;
    a Protein: .
  
  sub:_3 occursIn: mesh:D002467, atcc:HTB-22.aspx, species:9606;
    rdf:object sub:_2;
    rdf:predicate belv:increases;
    rdf:subject sub:_1;
    a rdf:Statement .
  
  sub:assertion rdfs:label "p(HGNC:NRG1) -> p(HGNC:CTNNB1)" .
}

sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements.";
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
    dce:title "BEL Framework Large Corpus Document";
    pav:authoredBy sub:_5;
    pav:version "1.4" .
  
  sub:_4 prov:value "To examine whether HRG signaling results in increased nuclear translocation of beta -catenin, we co-stained control and HRG-activated (30 min) cells with E-cadherin- and beta -catenin-specific antibodies and analyzed by confocal microscopy (Fig. 1D). We found that in addition to an increase within the cytoplasm, there was a significant enhancement of beta -catenin immunostaining inside the nucleus of HRG-treated cells (Fig. 1, lower panel). This was accompanied by cell-shape changes with appearance of some beta -catenin and E-cadherin immunoreactivity at the cellular free edges (Fig. 1D, arrows). In contrast, in control untreated cells, beta -catenin was almost exclusively restricted at the level of intercellular junctions (Fig. 1D, upper panel).";
    prov:wasQuotedFrom pubmed:11328805 .
  
  sub:_5 rdfs:label "Selventa" .
  
  sub:assertion prov:hadPrimarySource pubmed:11328805;
    prov:wasDerivedFrom beldoc:, sub:_4 .
}

sub:pubinfo {
  this: dct:created "2014-07-03T14:29:55.779+02:00"^^xsd:dateTime;
    pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}