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Approximately 61,000 statements.
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Copyright (c) 2011-2012, Selventa. All rights reserved.
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Thus, cardiac PI3Kgamma participates in two distinct signaling pathways: a kinase-dependent activity that controls PKB/Akt as well as MAPK phosphorylation and contributes to TAC-induced cardiac remodeling, and a kinase-independent activity that relies on protein interactions to regulate PDE3B activity and negatively modulates cardiac contractility.
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2014-07-03T14:30:26.535+02:00
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