. . . . . . . . . . . . . . . . . . . . "complex(p(HGNC:S100B),p(HGNC:AGER)) => cat(p(HGNC:AGER))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "TABLE 4 Downregulated genes in HMEC-4 cells after treatment with S100b Gene name AN Fold change Potential function -------------------------------------------------------------------------------- Stress response proteins Metallothionein 1E \t\t\t\t\tM10942 \t\t-2.3 Binds toxic metals and scavenges free radicals Similar to metallothionein 1E \t\t\tAL031602 \t-2.6 See function of metallothionein 1E Selenoprotein W, 1 (SEPW1) \t\t\t\tNM_003009 \t-2.1 Antioxidant Enzymes RNA polymerase II (DNA directed) polypeptide A \tNM_000937 \t-2.7 Largest subunit of RNA polymerase II (220 kD) Short-chain dehydrogenase reductase 1 (SDR1) \tNM_004753 \t-2.5 Regeneration of retinol (Vit. A) from retinal Highly similar to transglutaminase 2 \t\tBC003551 \t-2.2 99% identical to transglutaminase 2, a protein cross-linking enzyme Ubiquitin protein ligase E3A \t\t\tNM_000462 \t-2.0 Protein ubiquitination Mitochondrial proteins Glutaminase C \t\t\t\t\tAF158555 \t-2.4 Converts L-glutamine to L-glutamate Cytoskeletal-associated protein Caldesmon 1 (CALD1) \t\t\t\t\tNM_033157 \t-2.0 Actomyosin regulatory protein Other proteins RNA binding protein BRUNOL3 \t\t\t\tU69546 \t\t-2.0 Translation repression Clone 24775 \t\t\t\t\t\tAF052169 \t-2.1 Role unknown In contrast, the alternate RAGE ligand, S100b, triggered an increase in endothelial mRNA expression of a variety of immune-related genes." . . "Selventa" . . . . "2014-07-03T14:30:21.029+02:00"^^ . . .