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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAbVfIVjdyxKwDsoulM2PAl3kCo2mTlQh8tiHzyShzI9Y#_8 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAbVfIVjdyxKwDsoulM2PAl3kCo2mTlQh8tiHzyShzI9Y#_7 http://www.w3.org/ns/prov#value TABLE 4 Downregulated genes in HMEC-4 cells after treatment with S100b Gene name AN Fold change Potential function -------------------------------------------------------------------------------- Stress response proteins Metallothionein 1E M10942 -2.3 Binds toxic metals and scavenges free radicals Similar to metallothionein 1E AL031602 -2.6 See function of metallothionein 1E Selenoprotein W, 1 (SEPW1) NM_003009 -2.1 Antioxidant Enzymes RNA polymerase II (DNA directed) polypeptide A NM_000937 -2.7 Largest subunit of RNA polymerase II (220 kD) Short-chain dehydrogenase reductase 1 (SDR1) NM_004753 -2.5 Regeneration of retinol (Vit. 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