sub:provenance { beldoc:dce:description "Approximately 61,000 statements." ; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ; dce:title "BEL Framework Large Corpus Document" ; pav:authoredBysub:_4 ; pav:version "1.4" . sub:_3prov:value "IKK-i is expressed mainly in immune cells, and is induced in response to proinflammatory cytokines such as tumor necrosis factor-alpha, IL-1 and IL-6, in addition to LPS. We examined whether other stimuli induce IKK-i expression. Stimulation of RAW264.7 cells with IL-6 and IFN-{gamma} induced IKK-i mRNA expression. IKK-i mRNA expression was up-regulated upon stimulation of thioglycollate-elicited peritoneal macrophages with TNF-{alpha}, IL-1ß, IFN-{gamma} and IL-6 in addition to LPS. In contrast, mRNA expression levels of IKK-{alpha} or IKK-ß were not augmented in response to these stimuli." ; prov:wasQuotedFrompubmed:10421793 . sub:_4rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:10421793 ; prov:wasDerivedFrombeldoc: , sub:_3 . }