@prefix this: . @prefix sub: . @prefix beldoc: . @prefix rdfs: . @prefix rdf: . @prefix xsd: . @prefix dct: . @prefix dce: . @prefix pav: . @prefix np: . @prefix belv: . @prefix prov: . @prefix chebi: . @prefix RNA: . @prefix mgi: . @prefix geneProductOf: . @prefix mesh: . @prefix occursIn: . @prefix species: . @prefix pubmed: . @prefix orcid: . sub:Head { this: np:hasAssertion sub:assertion; np:hasProvenance sub:provenance; np:hasPublicationInfo sub:pubinfo; a np:Nanopublication . } sub:assertion { sub:_1 geneProductOf: mgi:1929612; a RNA: . sub:_2 occursIn: mesh:D008264, species:10090; rdf:object sub:_1; rdf:predicate belv:increases; rdf:subject chebi:6494; a rdf:Statement . sub:assertion rdfs:label "a(CHEBI:lipopolysaccharide) -> r(MGI:Ikbke)" . } sub:provenance { beldoc: dce:description "Approximately 61,000 statements."; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved."; dce:title "BEL Framework Large Corpus Document"; pav:authoredBy sub:_4; pav:version "1.4" . sub:_3 prov:value "IKK-i is expressed mainly in immune cells, and is induced in response to proinflammatory cytokines such as tumor necrosis factor-alpha, IL-1 and IL-6, in addition to LPS. We examined whether other stimuli induce IKK-i expression. Stimulation of RAW264.7 cells with IL-6 and IFN-{gamma} induced IKK-i mRNA expression. IKK-i mRNA expression was up-regulated upon stimulation of thioglycollate-elicited peritoneal macrophages with TNF-{alpha}, IL-1ß, IFN-{gamma} and IL-6 in addition to LPS. In contrast, mRNA expression levels of IKK-{alpha} or IKK-ß were not augmented in response to these stimuli."; prov:wasQuotedFrom pubmed:10421793 . sub:_4 rdfs:label "Selventa" . sub:assertion prov:hadPrimarySource pubmed:10421793; prov:wasDerivedFrom beldoc:, sub:_3 . } sub:pubinfo { this: dct:created "2014-07-03T14:29:47.749+02:00"^^xsd:dateTime; pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 . }