sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_5 ;
    pav:version "1.4" .
  sub:_4 prov:value "NF-?B also controls expression of other genes, the activities of which are linked to the invasive and metastatic behavior of cancer cells (Fig. 1). For example, NF-?B regulates expression of matrix metalloproteinase-9 (MMP-9), which is responsible for the degradation of tissue barriers [37]; cyclin D1, a cell cycle regulatory protein, which stimulates dysregulation of the cell cycle and tumor formation [38]; cell survival proteins Bcl-2 and BclXL, which protect against apoptosis of cancer cells [39]; and vascular endothelial growth factor (VEGF), which is a potent angiogenic factor stimulating tumor growth [40]. Based on the biological effects of NF-?B?regulated genes in cancer growth, invasion and metastasis, NF-?B has been suggested as a potential target for cancer therapies [41]." ;
    prov:wasQuotedFrom pubmed:15180498 .
  sub:_5 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:15180498 ;
    prov:wasDerivedFrom beldoc: , sub:_4 .
}