@prefix this: <
http://www.tkuhn.ch/bel2nanopub/RAcjpCfzGKE38My89xThW_G_UYM7QSe-ZO0lmFf75zAN0
> .
@prefix sub: <
http://www.tkuhn.ch/bel2nanopub/RAcjpCfzGKE38My89xThW_G_UYM7QSe-ZO0lmFf75zAN0#
> .
@prefix beldoc: <
http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix dct: <
http://purl.org/dc/terms/
> .
@prefix dce: <
http://purl.org/dc/elements/1.1/
> .
@prefix pav: <
http://purl.org/pav/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix belv: <
http://www.selventa.com/vocabulary/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix hgnc: <
http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=
> .
@prefix proteinModification: <
http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:00000
> .
@prefix psimod: <
http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:
> .
@prefix go: <
http://amigo.geneontology.org/amigo/term/GO:
> .
@prefix Protein: <
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080
> .
@prefix geneProductOf: <
http://purl.obolibrary.org/obo/RO_0002204
> .
@prefix hasAgent: <
http://semanticscience.org/resource/SIO_000139
> .
@prefix species: <
http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=
> .
@prefix occursIn: <
http://purl.obolibrary.org/obo/BFO_0000066
> .
@prefix pubmed: <
http://www.ncbi.nlm.nih.gov/pubmed/
> .
@prefix orcid: <
http://orcid.org/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
sub:_1
belv:variantOf
hgnc:9065
;
a
proteinModification:
,
psimod:00696
.
sub:_2
hasAgent:
sub:_3
;
a
go:0003824
.
sub:_3
geneProductOf:
hgnc:9065
;
a
Protein:
.
sub:_4
occursIn:
species:9606
;
rdf:object
sub:_2
;
rdf:predicate
belv:directlyIncreases
;
rdf:subject
sub:_1
;
a
rdf:Statement
.
sub:assertion
rdfs:label
"p(HGNC:PLCG1,pmod(P,Y,783)) => cat(p(HGNC:PLCG1))" .
}
sub:provenance
{
beldoc:
dce:description
"Approximately 61,000 statements." ;
dce:rights
"Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title
"BEL Framework Large Corpus Document" ;
pav:authoredBy
sub:_6
;
pav:version
"1.4" .
sub:_5
prov:value
"Despite extensive overlap in the molecules recruited to the active receptors, there is some preferential modulation of signalling pathways. Tumour cells that express EGFR with kinase-domain mutations preferentially activate the pro-survival PI3K?AKT and signal transducer and activator of transcription (STAT) pathways67. Although EGFR has no consensus sequence for the p85 adaptor subunit of PI3K, it couples to this pathway through GAB1, which binds growth-factorreceptor- bound protein 2 (GRB2)." ;
prov:wasQuotedFrom
pubmed:15864276
.
sub:_6
rdfs:label
"Selventa" .
sub:assertion
prov:hadPrimarySource
pubmed:15864276
;
prov:wasDerivedFrom
beldoc:
,
sub:_5
.
}
sub:pubinfo
{
this:
dct:created
"2014-07-03T14:30:34.850+02:00"^^
xsd:dateTime
;
pav:createdBy
orcid:0000-0001-6818-334X
,
orcid:0000-0002-1267-0234
.
}