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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAcmaEB8jTNH87b-VfyHZIZKST6Z2Rq1lDxNbmFjzVa3A#_8 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAcmaEB8jTNH87b-VfyHZIZKST6Z2Rq1lDxNbmFjzVa3A#_7 http://www.w3.org/ns/prov#value Conversely, insulin-stimulated PI(3)K activity was increased by 80% in muscle of both Rbp+/- and Rbp4-/- mice compared with control mice (Fig. 5b). However, PI(3)K activity was not altered in the liver of RBP4-Tg (Fig. 5c) or Rbp4-/- mice (Fig. 5d). Consistent with these observations, RBP4 injection for 21 days in wild-type mice caused a 34% reduction in insulin-stimulated PI(3)K activity in muscle, but no alteration in liver (Fig. 5e). 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