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[At the pre-B cell stage of lymphocyte development, immunoglobulin light-chains are not yet produced, and heavy-chains are covalently linked to surrogate light-chains composed of VpreB and ?5 to form the pre-B cell receptor (pre-BCR) in a non-covalent association with signal-transducing modules.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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