. . . . . . . . . . . . . . . . . "cat(p(HGNC:SIRT1)) -| tscript(p(HGNC:EP300))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "Herein, SIRT1 physically interacted with and repressed p300 transactivation, requiring the NAD-dependent deacetylase activity of SIRT1. SIRT1 repression involved the CRD1 transcriptional repression domain of p300. Two residues within the CRD1 domain (Lys-1020 and Lys-1024) were required for SIRT1 repression and served as substrates for SIRT1 deacetylation." . . "Selventa" . . . . "2014-07-03T14:30:30.667+02:00"^^ . . .