@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAcztzBdCmSxBBrNL2aYjKJGlvZki7ymmxJxrtbSTsmfQ> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAcztzBdCmSxBBrNL2aYjKJGlvZki7ymmxJxrtbSTsmfQ#> .
@prefix beldoc: <http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix hasPart: <http://purl.obolibrary.org/obo/BFO_0000051> .
@prefix ProteinComplex: <http://amigo.geneontology.org/amigo/term/GO:0043234> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix hasAgent: <http://semanticscience.org/resource/SIO_000139> .
@prefix hasAnnotation: <http://semanticscience.org/resource/SIO_000255> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix mesh: <http://purl.bioontology.org/ontology/MSH/> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  sub:_1 hasPart: sub:_2, sub:_3;
    a ProteinComplex: .
  
  sub:_2 geneProductOf: hgnc:4910;
    a Protein: .
  
  sub:_3 geneProductOf: hgnc:2348;
    a Protein: .
  
  sub:_4 hasAgent: sub:_5;
    a go:0042789 .
  
  sub:_5 geneProductOf: hgnc:4910;
    a Protein: .
  
  sub:_6 occursIn: mesh:D002292, species:9606;
    hasAnnotation: sub:_7;
    rdf:object sub:_4;
    rdf:predicate belv:directlyIncreases;
    rdf:subject sub:_1;
    a rdf:Statement .
  
  sub:_7 dcterms:subject "TextLocation";
    rdf:value "Legend" .
  
  sub:assertion rdfs:label "complex(p(HGNC:HIF1A),p(HGNC:CREBBP)) => tscript(p(HGNC:HIF1A))" .
}

sub:provenance {
  beldoc: dce:description "Approximately 2000 hand curated statements drawn from 57 PubMeds.";
    dce:rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved.";
    dce:title "BEL Framework Small Corpus Document";
    dcterms:license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License";
    pav:authoredBy sub:_9;
    pav:version "1.6" .
  
  sub:_8 prov:value """In a second hydroxylation-dependent control, b-hydroxylation of an asparaginyl residue
in the C-terminal activation domain of HIF-a (N803 in human HIF-1a) is regulated
by a HIF asparaginyl hydroxylase called FIH (factor inhibiting HIF) [62,63].
Hydroxylation at this site prevents the binding of the transcriptional co-activators
p300/CBP (CREB binding protein). Under normoxic conditions, these hydroxylation
reactions provide a dual mechanism for HIF inactivation that involves proteolytic
destruction and the inhibition of transcriptional activity [64].""";
    prov:wasQuotedFrom pubmed:15350900 .
  
  sub:_9 rdfs:comment "support@belframework.org";
    rdfs:label "Selventa" .
  
  sub:assertion prov:hadPrimarySource pubmed:15350900;
    prov:wasDerivedFrom beldoc:, sub:_8 .
}

sub:pubinfo {
  this: dcterms:created "2014-07-03T14:29:30.168+02:00"^^xsd:dateTime;
    pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}