@prefix dc: .
@prefix this: .
@prefix sub: .
@prefix beldoc: .
@prefix rdfs: .
@prefix rdf: .
@prefix xsd: .
@prefix dce: .
@prefix pav: .
@prefix np: .
@prefix belv: .
@prefix prov: .
@prefix go: .
@prefix Protein: .
@prefix hgnc: .
@prefix geneProductOf: .
@prefix hasAgent: .
@prefix species: .
@prefix occursIn: .
@prefix orcid: .
sub:Head {
this: np:hasAssertion sub:assertion;
np:hasProvenance sub:provenance;
np:hasPublicationInfo sub:pubinfo;
a np:Nanopublication .
}
sub:assertion {
sub:_1 hasAgent: sub:_2;
a go:0042789 .
sub:_2 geneProductOf: hgnc:3373;
a Protein: .
sub:_3 hasAgent: sub:_4;
a go:0042789 .
sub:_4 geneProductOf: hgnc:4910;
a Protein: .
sub:_5 occursIn: species:9606;
rdf:object sub:_3;
rdf:predicate belv:directlyIncreases;
rdf:subject sub:_1;
a rdf:Statement .
sub:assertion rdfs:label "tscript(p(HGNC:EP300)) => tscript(p(HGNC:HIF1A))" .
}
sub:provenance {
beldoc: dce:description "Approximately 61,000 statements.";
dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
dce:title "BEL Framework Large Corpus Document";
pav:authoredBy sub:_8;
pav:version "1.4" .
sub:_6 dce:identifier "Entrez Gene summary: EP300";
dce:title "Entrez Gene summary: EP300";
dce:type "Online Resource" .
sub:_7 prov:value "Entrez Gene summary: Human: EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CBP (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CBP can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.";
prov:wasQuotedFrom sub:_6 .
sub:_8 rdfs:label "Selventa" .
sub:assertion prov:hadPrimarySource sub:_6;
prov:wasDerivedFrom beldoc:, sub:_7 .
}
sub:pubinfo {
this: dc:created "2014-07-03T14:29:44.111+02:00"^^xsd:dateTime;
pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}