sub:provenance {
beldoc: dce:description "Approximately 2000 hand curated statements drawn from 57 PubMeds." ;
dce:rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved." ;
dce:title "BEL Framework Small Corpus Document" ;
dc:license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" ;
pav:authoredBy sub:_7 ;
pav:version "20131211" .
sub:_6 prov:value """Real-time PCR primers were designed for the PGC-1α 3' untranslated region that allows
for determination of the levels of ectopically expressed and endogenous PGC-1α.
As shown in Fig. 4B and as expected, ectopic PGC-1α is detected only in the
muscle of transgenic mice. Strikingly, a 7-fold elevation of endogenous PGC-1α
mRNA was seen in the transgenic animals as compared with wild-type mice (Fig. 4B).
A robust increase in the transcript levels of cytochrome c and myoglobin also
was observed in the RNA isolated from skeletal muscle of the transgenic mice,
whereas GAPDH transcript levels remained unchanged (Fig. 4B). These results indicate
a regulation of PGC-1α transcription by PGC-1α protein in an apparent autoregulatory
loop.""" ;
prov:wasQuotedFrom pubmed:12764228 .
sub:_7 rdfs:comment "support@belframework.org" ;
rdfs:label "Selventa" .
sub:assertion prov:hadPrimarySource pubmed:12764228 ;
prov:wasDerivedFrom beldoc: ,
sub:_6 .
}