@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAdIUI2Qs1HIL1VBYuSuTA7saUEMTRn7qx1hD7OPGuqYM> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAdIUI2Qs1HIL1VBYuSuTA7saUEMTRn7qx1hD7OPGuqYM#> .
@prefix beldoc: <http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix nch: <http://resource.belframework.org/belframework/1.0/namespace/selventa-named-human-complexes/> .
@prefix hasAgent: <http://semanticscience.org/resource/SIO_000139> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .
sub:Head {
   this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
   sub:_1 geneProductOf: hgnc:5246 ;
    a Protein: .
  sub:_2 geneProductOf: hgnc:11892 ;
    a Protein: .
  sub:_3 hasAgent: sub:_4 ;
    a go:0008233 .
  sub:_4 geneProductOf: nch:Proteasome%20Complex ;
    a Protein: .
  sub:_5 rdf:object sub:_3 ;
    rdf:predicate belv:increases ;
    rdf:subject sub:_2 ;
    a rdf:Statement .
  sub:_6 occursIn: species:9606 ;
    rdf:object sub:_5 ;
    rdf:predicate belv:increases ;
    rdf:subject sub:_1 ;
    a rdf:Statement .
  sub:assertion rdfs:label "p(HGNC:HSPB1) -> (p(HGNC:TNF) -> pep(p(NCH:\"Proteasome Complex\")))" , "p(HGNC:TNF) -> pep(p(NCH:\"Proteasome Complex\"))" .
}
sub:provenance {
   beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_8 ;
    pav:version "1.4" .
  sub:_7 prov:value "Here we show that HSP27 overexpression in various cell types enhances the degradation of ubiquitinated proteins by the 26S proteasome in response to stressful stimuli, such as etoposide or tumor necrosis factor alpha (TNF-alpha). We demonstrate that HSP27 binds to polyubiquitin chains and to the 26S proteasome in vitro and in vivo" ;
    prov:wasQuotedFrom pubmed:12897149 .
  sub:_8 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:12897149 ;
    prov:wasDerivedFrom beldoc: , sub:_7 .
}
sub:pubinfo {
   this: dct:created "2014-07-03T14:30:15.335+02:00"^^xsd:dateTime ;
    pav:createdBy orcid:0000-0001-6818-334X , orcid:0000-0002-1267-0234 .
}