sub:provenance {
  beldoc: dce:description "Approximately 2000 hand curated statements drawn from 57 PubMeds." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved." ;
    dce:title "BEL Framework Small Corpus Document" ;
    dcterms:license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" ;
    pav:authoredBy sub:_8 ;
    pav:version "1.6" .
  sub:_7 prov:value """The activation of B-Raf by Ras has been less well studied; however, the interacting
amino acids in the Ras-Raf interface are identical for B-Raf and C-Raf.129,130
The association of Ras with B-Raf also translocates B-Raf to the cell membrane
where it is activated.124  Interestingly, a membrane-free complex of B-Raf and
14-3-3 can be activated in vitro by recombinant Ras. This is in stark contrast
to A-Raf and C-Raf, which must undergo a series of phosphorylation reactions on
serine and tyrosine residues in the cell membrane and cannot be activated by Ras
alone.124,130  Of the Raf isoforms, B-Raf is activated first, and on stimulation
by Ras, it heterodimerizes with C-Raf, the significance of which is not known.94""" ;
    prov:wasQuotedFrom pubmed:16170185 .
  sub:_8 rdfs:comment "support@belframework.org" ;
    rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:16170185 ;
    prov:wasDerivedFrom beldoc: , sub:_7 .
}