@prefix this: . @prefix sub: . @prefix beldoc: . @prefix rdfs: . @prefix rdf: . @prefix xsd: . @prefix dct: . @prefix dce: . @prefix pav: . @prefix np: . @prefix belv: . @prefix prov: . @prefix go: . @prefix Protein: . @prefix mgi: . @prefix geneProductOf: . @prefix hasAgent: . @prefix species: . @prefix occursIn: . @prefix mesh: . @prefix pubmed: . @prefix orcid: . sub:Head { this: np:hasAssertion sub:assertion; np:hasProvenance sub:provenance; np:hasPublicationInfo sub:pubinfo; a np:Nanopublication . } sub:assertion { sub:_1 hasAgent: sub:_2; a go:0003824 . sub:_2 geneProductOf: mgi:1888594; a Protein: . sub:_3 geneProductOf: mgi:104798; a Protein: . sub:_4 hasAgent: sub:_5; a go:0005525 . sub:_5 geneProductOf: mgi:97845; a Protein: . sub:_6 rdf:object sub:_4; rdf:predicate belv:increases; rdf:subject sub:_3; a rdf:Statement . sub:_7 occursIn: mesh:D004727, species:10090; rdf:object sub:_6; rdf:predicate belv:increases; rdf:subject sub:_1; a rdf:Statement . sub:assertion rdfs:label "cat(p(MGI:Icmt)) -> (p(MGI:Tnf) -> gtp(p(MGI:Rac1)))", "p(MGI:Tnf) -> gtp(p(MGI:Rac1))" . } sub:provenance { beldoc: dce:description "Approximately 61,000 statements."; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved."; dce:title "BEL Framework Large Corpus Document"; pav:authoredBy sub:_9; pav:version "1.4" . sub:_8 prov:value "TNF alpha stimulation of EC increased the membrane association of Rac1, an event that is essential for Rac1 activity. ICMT inhibitor N-acetyl-S-farnesyl-L-cysteine (AFC) blocked the accumulation of Rac1 into the membrane both in resting and TNF alpha-stimulated conditions. Similarly, the membrane-associated Rac1 was lower in Icmt-deficient versus wild-type mouse embryonic fibroblasts (MEFs)."; prov:wasQuotedFrom pubmed:15647276 . sub:_9 rdfs:label "Selventa" . sub:assertion prov:hadPrimarySource pubmed:15647276; prov:wasDerivedFrom beldoc:, sub:_8 . } sub:pubinfo { this: dct:created "2014-07-03T14:30:30.880+02:00"^^xsd:dateTime; pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 . }