sub:provenance { beldoc:dce:description "Approximately 61,000 statements." ; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ; dce:title "BEL Framework Large Corpus Document" ; pav:authoredBysub:_8 ; pav:version "1.4" . sub:_7prov:value "Transcriptional activation involves alterations in chromatin structure mediated by ATP-dependent chromatin-remodeling enzymes in conjunction with factors that contain histone acetyltransferase (HAT) activity [17]. Consistent with this concept is the observation that ER recruits BRG1, a mammalian homologue of a component of the SWI/SNF chromatin remodeling complex, to EREs in a cooperative manner with HATs [18]. Further, many ER coactivators possess intrinsic HAT activities, including CBP/p300, p/CAF, and TAFII250 [19-21]. Other coactivators such as the p160 coactivators facilitate ER transcription by serving as platforms to recruit HATs and protein methyltransferases." ; prov:wasQuotedFrompubmed:14680484 . sub:_8rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:14680484 ; prov:wasDerivedFrombeldoc: , sub:_7 . }