http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ#head http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ http://www.nanopub.org/nschema#hasAssertion http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ#assertion http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ http://www.nanopub.org/nschema#hasProvenance http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ#provenance http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ http://www.nanopub.org/nschema#hasPublicationInfo http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ#publicationInfo http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ#assertion http://rdf.disgenet.org/resource/gda/DGN08871f6bd06e0c98988702dabe0e6b52 http://semanticscience.org/resource/SIO_000628 http://identifiers.org/ncbigene/7157 http://rdf.disgenet.org/resource/gda/DGN08871f6bd06e0c98988702dabe0e6b52 http://semanticscience.org/resource/SIO_000628 http://linkedlifedata.com/resource/umls/id/C0242379 http://rdf.disgenet.org/resource/gda/DGN08871f6bd06e0c98988702dabe0e6b52 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://semanticscience.org/resource/SIO_001122 http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ#provenance http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ#assertion http://purl.org/dc/terms/description [Our results show: (1) wild-type p53 stimulates the transcription of reporter genes with p53CON and RGC in their 5' region while most p53 mutants occurring in human cancers have lost this activity; (2) the R273H mutant retains transcriptional activity for the p53CON sequence but not RGC; (3) some mutants are temperature-sensitive for the transcriptional activity with the p53CON but not the RGC sequence; (4) p53 mutants vary in their ability to inhibit wild-type p53 transactivation but there is no difference between p53CON and RGC sequences; (5) lung cancer cells with endogenous mutant p53 proteins (M246I in H23 cells and R248L in H322 cells) retain transcriptional activity for the p53CON but not the RGC sequence.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine. http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ#assertion http://purl.org/ontology/wi/core#evidence http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ#assertion http://semanticscience.org/resource/SIO_000772 http://identifiers.org/pubmed/8336941 http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://rdf.disgenet.org/v5.0.0/void/BEFREE http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ#assertion http://www.w3.org/ns/prov#wasGeneratedBy http://purl.obolibrary.org/obo/ECO_0000203 http://rdf.disgenet.org/v5.0.0/void/BEFREE http://purl.org/pav/importedOn 2017-02-19 http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.obolibrary.org/obo/ECO_0000212 http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#comment Gene-disease associations inferred from text-mining the literature. http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#label DisGeNET evidence - LITERATURE http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ#publicationInfo http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ http://purl.org/dc/terms/created 2017-10-17T13:16:57+02:00 http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ http://purl.org/dc/terms/rights http://opendatacommons.org/licenses/odbl/1.0/ http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ http://purl.org/dc/terms/rightsHolder http://rdf.disgenet.org/v5.0.0/void/IBIGroup http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ http://purl.org/dc/terms/subject http://semanticscience.org/resource/SIO_000983 http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ http://purl.org/net/provenance/ns#usedData http://rdf.disgenet.org/v5.0.0/void/disgenetv3.0rdf http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ http://purl.org/pav/authoredBy http://orcid.org/0000-0001-5999-6269 http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ http://purl.org/pav/authoredBy http://orcid.org/0000-0002-7534-7661 http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ http://purl.org/pav/authoredBy http://orcid.org/0000-0002-9383-528X http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ http://purl.org/pav/authoredBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ http://purl.org/pav/authoredBy http://orcid.org/0000-0003-1244-7654 http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ http://purl.org/pav/createdBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP1062007.RAdo2T2Jz0eTzgtWGaiyoAU2WKm4aVnFYlZvRwshlylXQ http://purl.org/pav/version v5.0.0.0 http://rdf.disgenet.org/v5.0.0/void/disgenetv3.0rdf http://purl.org/pav/version v5.0.0