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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAdvS9aCLpZ49miRjA3YCfcKey-gdJz2qE3ek1xdhel4M#_4 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAdvS9aCLpZ49miRjA3YCfcKey-gdJz2qE3ek1xdhel4M#_3 http://www.w3.org/ns/prov#value It was found that the inhibition of Akt, mediated by K10 expression, leads to impaired NF-kappa B activity. This appears to occur through the decreased expression of IKK beta and IKK gamma. Remarkably, increased production of tumor necrosis factor alpha and concomitant JNK activation was observed in the epidermis of these transgenic mice. http://www.tkuhn.ch/bel2nanopub/RAdvS9aCLpZ49miRjA3YCfcKey-gdJz2qE3ek1xdhel4M#_3 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/12566451 http://www.tkuhn.ch/bel2nanopub/RAdvS9aCLpZ49miRjA3YCfcKey-gdJz2qE3ek1xdhel4M#_4 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAdvS9aCLpZ49miRjA3YCfcKey-gdJz2qE3ek1xdhel4M#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/12566451 http://www.tkuhn.ch/bel2nanopub/RAdvS9aCLpZ49miRjA3YCfcKey-gdJz2qE3ek1xdhel4M#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAdvS9aCLpZ49miRjA3YCfcKey-gdJz2qE3ek1xdhel4M#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAdvS9aCLpZ49miRjA3YCfcKey-gdJz2qE3ek1xdhel4M#_3 http://www.tkuhn.ch/bel2nanopub/RAdvS9aCLpZ49miRjA3YCfcKey-gdJz2qE3ek1xdhel4M#pubinfo http://www.tkuhn.ch/bel2nanopub/RAdvS9aCLpZ49miRjA3YCfcKey-gdJz2qE3ek1xdhel4M http://purl.org/dc/terms/created 2014-07-03T14:30:09.838+02:00 http://www.tkuhn.ch/bel2nanopub/RAdvS9aCLpZ49miRjA3YCfcKey-gdJz2qE3ek1xdhel4M http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAdvS9aCLpZ49miRjA3YCfcKey-gdJz2qE3ek1xdhel4M http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234