. . . . . . . . . . . . "path(SDIS:\"laminar shear stress\") -> p(HGNC:CDKN1A)" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "Laminar shear stress suppresses the G1- to S-phase transition in ECs,10,11 and this is associated with an increase in the expression of p21, an inhibitor of cyclin-dependent kinases (cdks), at mRNA and protein levels. These changes are accompanied by decreases in the phosphorylation of retinoblastoma protein (Rb) and the activities of cdk2 and cdk4.10,11" . . "Selventa" . . . . "2014-07-03T14:30:06.894+02:00"^^ . . .