sub:provenance { beldoc:dce:description "Approximately 61,000 statements." ; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ; dce:title "BEL Framework Large Corpus Document" ; pav:authoredBysub:_4 ; pav:version "1.4" . sub:_3prov:value "Additional evidence of the involvement of these inflammatory pathways is supported by the protective effect of some anti-inflammatory drugs against obesity-induced insulin resistance. Aspirin may inhibit not only IKK and JNK (93,94) but other Ser/Thr kinases (mamalian target of rapamycin and protein kinase B/Akt) related to TNF-alpha insulin resistance by phosphorylation of IRS-1 at serine residues (94). Furthermore, through its antioxidant properties, aspirin has been shown to reduce the activation of NF-kappaB or AP-1 associated with reactive oxygen species (95)." ; prov:wasQuotedFrompubmed:15793228 . sub:_4rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:15793228 ; prov:wasDerivedFrombeldoc: , sub:_3 . }