sub:provenance { beldoc:dce:description "Approximately 61,000 statements." ; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ; dce:title "BEL Framework Large Corpus Document" ; pav:authoredBysub:_5 ; pav:version "1.4" . sub:_4prov:value "Several reports have demonstrated that the inactivation of pVHL tumour suppressor function is linked to abnormal extracellular fibronectin arrays in both RCC cells that lack functional pVHL and VHLK-K mouse fibroblasts [44 to 46]. However, the exact nature of such an association and the mechanism by which VHL regulates the assembly of this ECM remain poorly understood. Nevertheless, the restored ability of pVHL-positive transfectants to assemble extracellular fibronectin was mediated by b1 integrins, implying that pVHL controls ECM assembly, at least in part, through integrin signalling [46]." ; prov:wasQuotedFrompubmed:15350900 . sub:_5rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:15350900 ; prov:wasDerivedFrombeldoc: , sub:_4 . }