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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAeMSm5OEyMGoQNXWM_I_jewWdZDq6PoWH93SjZt8E0Dc#_4 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAeMSm5OEyMGoQNXWM_I_jewWdZDq6PoWH93SjZt8E0Dc#_3 http://www.w3.org/ns/prov#value Here, human lymphoid cells (Jurkat cells) were used to model effects of cellular flavin supply on secretion of IL-2 (containing one disulfide bond) and cellular stress response. Cells were cultured in media containing 0.85, 3.1, 12.6 or 300.6 nmol/L riboflavin for 5 wk, representing severely deficient, moderately deficient, physiologic and pharmacologic plasma concentrations in humans, respectively.... Intracellular accumulation of IL-2 was greater in severely deficient cells than in other groups. http://www.tkuhn.ch/bel2nanopub/RAeMSm5OEyMGoQNXWM_I_jewWdZDq6PoWH93SjZt8E0Dc#_3 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/12612135 http://www.tkuhn.ch/bel2nanopub/RAeMSm5OEyMGoQNXWM_I_jewWdZDq6PoWH93SjZt8E0Dc#_4 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAeMSm5OEyMGoQNXWM_I_jewWdZDq6PoWH93SjZt8E0Dc#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/12612135 http://www.tkuhn.ch/bel2nanopub/RAeMSm5OEyMGoQNXWM_I_jewWdZDq6PoWH93SjZt8E0Dc#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAeMSm5OEyMGoQNXWM_I_jewWdZDq6PoWH93SjZt8E0Dc#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAeMSm5OEyMGoQNXWM_I_jewWdZDq6PoWH93SjZt8E0Dc#_3 http://www.tkuhn.ch/bel2nanopub/RAeMSm5OEyMGoQNXWM_I_jewWdZDq6PoWH93SjZt8E0Dc#pubinfo http://www.tkuhn.ch/bel2nanopub/RAeMSm5OEyMGoQNXWM_I_jewWdZDq6PoWH93SjZt8E0Dc http://purl.org/dc/terms/created 2014-07-03T14:30:10.641+02:00 http://www.tkuhn.ch/bel2nanopub/RAeMSm5OEyMGoQNXWM_I_jewWdZDq6PoWH93SjZt8E0Dc http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAeMSm5OEyMGoQNXWM_I_jewWdZDq6PoWH93SjZt8E0Dc http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234