sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_8 ;
    pav:version "1.4" .
  sub:_7 prov:value "To test whether pRb is required for MyoD to activate the MEF2C TAD, we transfected Rb-/- fibroblasts with the Gal4-MEF2C fusion protein either alone or with MyoD and E12, in either the absence or the presence of exogenous pRb. When expressed alone, MyoD+E12 did not significantly stimulate Gal4-MEF2C function in these cells (Figure 3c, column 4). Similarly, the expression of pRb alone did not affect the activity of Gal4-MEF2C (Figure 3c, column 5); but, the combined expression of MyoD+E12 and pRb led to a 45-fold increase in the activity of Gal4-MEF2C (Figure 3c, column 6). These findings indicate that MyoDmediated activation of the MEF2C TAD requires pRb." ;
    prov:wasQuotedFrom pubmed:10322110 .
  sub:_8 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:10322110 ;
    prov:wasDerivedFrom beldoc: , sub:_7 .
}