. . . . . . . . . . . . . . . . . . . . . "complex(p(HGNC:INSR),p(HGNC:IRS1)) => cat(p(HGNC:IRS1))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "TNF-{alpha} reduces insulin-stimulated receptor tyrosine kinase activity at low concentrations and can also decrease the expression of the insulin receptor, IRS-1 and GLUT-4 at higher concentrations (22) as well as increase the phosphorylation of serine 307 of IRS-1, thus impairing its ability to bind to the insulin receptor and initiate downstream signaling." . . "Selventa" . . . . "2014-07-03T14:30:16.119+02:00"^^ . . .