. . . . . . . . . . . . . . . "kin(p(PFH:\"PRKC Family\")) -> r(HGNC:PLAU)" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "Increased expression of PKC in malignant and aggressive breast cancers was recently demonstrated, and PKC activity has been shown to be higher in breast cancers than in normal breast tissue [68, 69]. In addition, high levels of PKC? and -? were correlated with enhanced uPA secretion in highly invasive MDA-MB- 231 breast cancer cells [70]. Furthermore, the introduction of PKC? gene to nonmetastatic MCF-7 breast cancer cells resulted in more aggressive neoplastic phenotype, and the stimulation of PKC activity with phorbol ester, phorbol-12- myristate-13-acetate (PMA), resulted in increases in both invasiveness and uPA expression" . . "Selventa" . . . . "2014-07-03T14:30:23.975+02:00"^^ . . .