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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAezrOklTogVd8Ne2Zwhysk3SXSlciqrxMPvyGh8jx-tU#_6 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAezrOklTogVd8Ne2Zwhysk3SXSlciqrxMPvyGh8jx-tU#_5 http://www.w3.org/ns/prov#value In vitro translated hBVR and nuclear extract containing hBVR in gel mobility-shift assay bound to AP-1 sites in the ATF-2 promoter region and to an oligonucleotide containing the CRE site. Both bindings could be competed out by excess unlabeled probe; in the presence of hBVR antibody, they displayed shifted bands. Co-transfection of hBVR with ATF-2 or c-jun promoters caused a severalfold increase in luciferase activity. hBVR modulation of ATF-2 and HO-1 expression suggests it has a potential role in regulation of AP-1 and cAMP-regulated genes and a role in cell signaling. http://www.tkuhn.ch/bel2nanopub/RAezrOklTogVd8Ne2Zwhysk3SXSlciqrxMPvyGh8jx-tU#_5 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/14988408 http://www.tkuhn.ch/bel2nanopub/RAezrOklTogVd8Ne2Zwhysk3SXSlciqrxMPvyGh8jx-tU#_6 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAezrOklTogVd8Ne2Zwhysk3SXSlciqrxMPvyGh8jx-tU#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/14988408 http://www.tkuhn.ch/bel2nanopub/RAezrOklTogVd8Ne2Zwhysk3SXSlciqrxMPvyGh8jx-tU#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAezrOklTogVd8Ne2Zwhysk3SXSlciqrxMPvyGh8jx-tU#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAezrOklTogVd8Ne2Zwhysk3SXSlciqrxMPvyGh8jx-tU#_5 http://www.tkuhn.ch/bel2nanopub/RAezrOklTogVd8Ne2Zwhysk3SXSlciqrxMPvyGh8jx-tU#pubinfo http://www.tkuhn.ch/bel2nanopub/RAezrOklTogVd8Ne2Zwhysk3SXSlciqrxMPvyGh8jx-tU http://purl.org/dc/terms/created 2014-07-03T14:30:21.060+02:00 http://www.tkuhn.ch/bel2nanopub/RAezrOklTogVd8Ne2Zwhysk3SXSlciqrxMPvyGh8jx-tU http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAezrOklTogVd8Ne2Zwhysk3SXSlciqrxMPvyGh8jx-tU http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234