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[Furthermore, ?-cryptoxanthin induced an accumulation of cells in the G1/G0 phase of the cell cycle (as detected by flow cytometry), which was in accordance with an increased expression of p21 and down regulations of cyclin D1 and cyclin E, detected by Western blot analysis, and ?-cryptoxanthin increased the mRNA levels of retinoic acid receptor ? (RAR?) with the treatment at 10 ?M for 24 h. Collectively, the above findings suggest that ?-cryptoxanthin could be therapeutic in the treatment of stomach cancer cell in vitro.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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