sub:provenance { beldoc:dce:description "Approximately 61,000 statements." ; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ; dce:title "BEL Framework Large Corpus Document" ; pav:authoredBysub:_6 ; pav:version "1.4" . sub:_5prov:value "Nrf1 and Nrf2 Regulate a Similar Subset of Antioxidant Genes: Expression of Gclm was reduced to the same extent in both Nrf1 and Nrf2 mutant cells. NQO1 was down-regulated to a similar extent in both single mutant cells, whereas mRNA levels of heme-oxygenase-1 (HO-1), ferritin-H (FtH), and metallothionein-1 (MT-1) was lower in nrf2–/– cells compared with nrf1–/– cells (Fig. 6a). In all cases, however, expression in double knockout cells was abolished compared with single knockout cells, indicating a dependence on both Nrf1 and Nrf2" ; prov:wasQuotedFrompubmed:12968018 . sub:_6rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:12968018 ; prov:wasDerivedFrombeldoc: , sub:_5 . }