@prefix this: <
http://www.tkuhn.ch/bel2nanopub/RAfDLsxYBS8FaTtG1CIGwArj4SVe9MDxiKJa8l_vmh-vQ
> .
@prefix sub: <
http://www.tkuhn.ch/bel2nanopub/RAfDLsxYBS8FaTtG1CIGwArj4SVe9MDxiKJa8l_vmh-vQ#
> .
@prefix beldoc: <
http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix dct: <
http://purl.org/dc/terms/
> .
@prefix dce: <
http://purl.org/dc/elements/1.1/
> .
@prefix pav: <
http://purl.org/pav/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix belv: <
http://www.selventa.com/vocabulary/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix Protein: <
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080
> .
@prefix mgi: <
http://www.informatics.jax.org/marker/MGI:
> .
@prefix geneProductOf: <
http://purl.obolibrary.org/obo/RO_0002204
> .
@prefix chebi: <
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=
> .
@prefix species: <
http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=
> .
@prefix occursIn: <
http://purl.obolibrary.org/obo/BFO_0000066
> .
@prefix pubmed: <
http://www.ncbi.nlm.nih.gov/pubmed/
> .
@prefix orcid: <
http://orcid.org/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
sub:_1
geneProductOf:
mgi:104767
;
a
Protein:
.
sub:_2
occursIn:
species:10090
;
rdf:object
chebi:6421
;
rdf:predicate
belv:decreases
;
rdf:subject
sub:_1
;
a
rdf:Statement
.
sub:assertion
rdfs:label
"p(MGI:Gpx4) -| a(CHEBI:\"leukotriene B4\")" .
}
sub:provenance
{
beldoc:
dce:description
"Approximately 61,000 statements." ;
dce:rights
"Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title
"BEL Framework Large Corpus Document" ;
pav:authoredBy
sub:_4
;
pav:version
"1.4" .
sub:_3
prov:value
"Overexpressed Gpx4 approximately threefold, the conversion of arachidonic acid to intermediates in the lipoxygenase pathway was inhibited eightfold (leukotriene C4 and leukotriene B4). Normal rates of leukotriene C4 formation were restored in the transfected cell by treatment with the inhibitor diethylmalate, which decreases GPX4 activity...The authors concluded that Gpx4 deactivated 5-lipoxygenase via decreases in levels of hydroperoxides required for activation of the enzyme." ;
prov:wasQuotedFrom
pubmed:11215509
.
sub:_4
rdfs:label
"Selventa" .
sub:assertion
prov:hadPrimarySource
pubmed:11215509
;
prov:wasDerivedFrom
beldoc:
,
sub:_3
.
}
sub:pubinfo
{
this:
dct:created
"2014-07-03T14:29:54.326+02:00"^^
xsd:dateTime
;
pav:createdBy
orcid:0000-0001-6818-334X
,
orcid:0000-0002-1267-0234
.
}