@prefix this: . @prefix sub: . @prefix beldoc: . @prefix rdfs: . @prefix rdf: . @prefix xsd: . @prefix dct: . @prefix dce: . @prefix pav: . @prefix np: . @prefix belv: . @prefix prov: . @prefix Protein: . @prefix mgi: . @prefix geneProductOf: . @prefix chebi: . @prefix species: . @prefix occursIn: . @prefix pubmed: . @prefix orcid: . sub:Head { this: np:hasAssertion sub:assertion; np:hasProvenance sub:provenance; np:hasPublicationInfo sub:pubinfo; a np:Nanopublication . } sub:assertion { sub:_1 geneProductOf: mgi:104767; a Protein: . sub:_2 occursIn: species:10090; rdf:object chebi:6421; rdf:predicate belv:decreases; rdf:subject sub:_1; a rdf:Statement . sub:assertion rdfs:label "p(MGI:Gpx4) -| a(CHEBI:\"leukotriene B4\")" . } sub:provenance { beldoc: dce:description "Approximately 61,000 statements."; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved."; dce:title "BEL Framework Large Corpus Document"; pav:authoredBy sub:_4; pav:version "1.4" . sub:_3 prov:value "Overexpressed Gpx4 approximately threefold, the conversion of arachidonic acid to intermediates in the lipoxygenase pathway was inhibited eightfold (leukotriene C4 and leukotriene B4). Normal rates of leukotriene C4 formation were restored in the transfected cell by treatment with the inhibitor diethylmalate, which decreases GPX4 activity...The authors concluded that Gpx4 deactivated 5-lipoxygenase via decreases in levels of hydroperoxides required for activation of the enzyme."; prov:wasQuotedFrom pubmed:11215509 . sub:_4 rdfs:label "Selventa" . sub:assertion prov:hadPrimarySource pubmed:11215509; prov:wasDerivedFrom beldoc:, sub:_3 . } sub:pubinfo { this: dct:created "2014-07-03T14:29:54.326+02:00"^^xsd:dateTime; pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 . }