. . . . . . . . . . . . . . . . . . . . . . "complex(p(HGNC:S100A8),p(HGNC:S100A9)) -> surf(p(HGNC:ITGAM))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "In this study, we report that S100A8, S100A9, and S100A8/A9 caused neutrophil chemotaxis at concentrations of 10(-12)-10(-9) M. S100A8, S100A9, and S100A8/A9 stimulated shedding of L-selectin, up-regulated and activated Mac-1, and induced neutrophil adhesion to fibrinogen in vitro. As shown in Fig. 3, MRPs induced shedding of L-selectin (CD62L) from the neutrophil surface. In contrast, expression of CD11b, but not CD51 was up-regulated following stimulation with MRPs. As Mac-1 is stored in specific and gelatinase granules, this suggests that MRPs induced neutrophil degranulation." . . "Selventa" . . . . "2014-07-03T14:30:10.744+02:00"^^ . . .