. . . . . . . . . . . . . . . . . "kin(p(MGI:Kdr)) -> p(MGI:Mapk1,pmod(P))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "Treatment of glEND.2 cells with vascular endothelial growth factor (VEGF, 10 ng/ml) induced a time dependent phosphorylation of ERK1/2, which was significant at 2 minutes of VEGF exposure (3.7 fold), peaking at 10 minutes, and thereafter tapering off. VEGF also induced activation of VEGFR-2. VEGF induced ERK1/2 activation was totally blocked by pretreatment with specific ERK1/2 inhibitor U0126. Inhibition of ERK1/2 activation also inhibited VEGF induced proliferation, where as inhibition of PKC or PI3K had no effect, suggesting that VEGF induces receptor mediated activation of ERK1/2 leading to proliferation in glEND.2 cells." . . "Selventa" . . . . "2014-07-03T14:30:36.986+02:00"^^ . . .