@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAgAdXbqgySARnM5gT4SkxXPtR6r-KQWD4F2OpNtL7S-w> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAgAdXbqgySARnM5gT4SkxXPtR6r-KQWD4F2OpNtL7S-w#> .
@prefix beldoc: <http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix nch: <http://resource.belframework.org/belframework/1.0/namespace/selventa-named-human-complexes/> .
@prefix ProteinComplex: <http://amigo.geneontology.org/amigo/term/GO:0043234> .
@prefix hasAgent: <http://semanticscience.org/resource/SIO_000139> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix atcc: <http://www.lgcstandards-atcc.org/Products/All/> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .
sub:Head {
   this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
   nch:Nfkb%20Complex a ProteinComplex: .
  sub:_1 geneProductOf: hgnc:11929 ;
    a Protein: .
  sub:_2 hasAgent: nch:Nfkb%20Complex ;
    a go:0042789 .
  sub:_3 occursIn: atcc:CRL-1593.2.aspx , species:9606 ;
    rdf:object sub:_2 ;
    rdf:predicate belv:increases ;
    rdf:subject sub:_1 ;
    a rdf:Statement .
  sub:assertion rdfs:label "p(HGNC:TNFSF13B) -> tscript(complex(NCH:\"Nfkb Complex\"))" .
}
sub:provenance {
   beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_5 ;
    pav:version "1.4" .
  sub:_4 prov:value "U937 cells were treated with different concentrations of TNFSF13B for 60 minutes at 37 degrees and then assayed for NFKB by EMSA. Also U937 cells were treated with 1 nanomolar of TNFSF13B for various lengths of time to assay the kinetics of NFKB activation all of which indicated that TNFSF13B activates NFKB in a dose and time dependent manner. The gel shift band was specific as its formation could be eliminated with excess unlabeled oligonucleotide and was supershifted by anti-p50 antibody only. To further ascertain NFKB activation was due to proteinaceous nature of TNFSF13B, protein was either digested with trypsin or heat-denatured prior to treatment, both of which completely abolished NFKB activation confirming that TNFSF13B was responsible for this activation." ;
    prov:wasQuotedFrom pubmed:10347144 .
  sub:_5 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:10347144 ;
    prov:wasDerivedFrom beldoc: , sub:_4 .
}
sub:pubinfo {
   this: dct:created "2014-07-03T14:29:47.260+02:00"^^xsd:dateTime ;
    pav:createdBy orcid:0000-0001-6818-334X , orcid:0000-0002-1267-0234 .
}