[ { "@graph" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAgC_0urg6div7fE1BF8Zn93lLk5zgSHLuzFds15e7OaU", "@type" : [ "http://www.nanopub.org/nschema#Nanopublication" ], "http://www.nanopub.org/nschema#hasAssertion" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAgC_0urg6div7fE1BF8Zn93lLk5zgSHLuzFds15e7OaU#assertion" } ], "http://www.nanopub.org/nschema#hasProvenance" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAgC_0urg6div7fE1BF8Zn93lLk5zgSHLuzFds15e7OaU#provenance" } ], "http://www.nanopub.org/nschema#hasPublicationInfo" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAgC_0urg6div7fE1BF8Zn93lLk5zgSHLuzFds15e7OaU#pubinfo" } ] } ], "@id" : "http://www.tkuhn.ch/bel2nanopub/RAgC_0urg6div7fE1BF8Zn93lLk5zgSHLuzFds15e7OaU#Head" }, { "@graph" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAgC_0urg6div7fE1BF8Zn93lLk5zgSHLuzFds15e7OaU#_1", "@type" : [ "http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_33697" ], "http://purl.obolibrary.org/obo/RO_0002204" : [ { "@id" : "http://rgd.mcw.edu/rgdweb/report/gene/main.html?id=2943" } ] }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAgC_0urg6div7fE1BF8Zn93lLk5zgSHLuzFds15e7OaU#_2", "@type" : [ "http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement" ], "http://purl.obolibrary.org/obo/BFO_0000066" : [ { "@id" : "http://purl.bioontology.org/ontology/MSH/D018482" }, { "@id" : "http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10116" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#object" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAgC_0urg6div7fE1BF8Zn93lLk5zgSHLuzFds15e7OaU#_1" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate" : [ { "@id" : "http://www.selventa.com/vocabulary/increases" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject" : [ { "@id" : "http://amigo.geneontology.org/amigo/term/GO:0014889" } ] }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAgC_0urg6div7fE1BF8Zn93lLk5zgSHLuzFds15e7OaU#assertion", "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "bp(GO:\"muscle atrophy\") -> r(RGD:Jun)" } ] } ], "@id" : "http://www.tkuhn.ch/bel2nanopub/RAgC_0urg6div7fE1BF8Zn93lLk5zgSHLuzFds15e7OaU#assertion" }, { "@graph" : [ { "@id" : "http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel", "http://purl.org/dc/elements/1.1/description" : [ { "@value" : "Approximately 61,000 statements." } ], "http://purl.org/dc/elements/1.1/rights" : [ { "@value" : "Copyright (c) 2011-2012, Selventa. All rights reserved." } ], "http://purl.org/dc/elements/1.1/title" : [ { "@value" : "BEL Framework Large Corpus Document" } ], "http://purl.org/pav/authoredBy" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAgC_0urg6div7fE1BF8Zn93lLk5zgSHLuzFds15e7OaU#_4" } ], "http://purl.org/pav/version" : [ { "@value" : "1.4" } ] }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAgC_0urg6div7fE1BF8Zn93lLk5zgSHLuzFds15e7OaU#_3", "http://www.w3.org/ns/prov#value" : [ { "@value" : "Among the strongly induced genes were many involved in protein degradation, including polyubiquitins, Ub fusion proteins, the Ub ligases atrogin-1/MAFbx and MuRF-1, multiple but not all subunits of the 20S proteasome and its 19S regulator, and cathepsin L. Many genes required for ATP production and late steps in glycolysis were down-regulated, as were many transcripts for extracellular matrix proteins. Some genes not previously implicated in muscle atrophy were dramatically up-regulated (lipin, metallothionein, AMP deaminase, RNA helicase-related protein, TG interacting factor) and several growth-related mRNAs were down-regulated (P311, JUN, IGF-1-BP5)" } ], "http://www.w3.org/ns/prov#wasQuotedFrom" : [ { "@id" : "http://www.ncbi.nlm.nih.gov/pubmed/14718385" } ] }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAgC_0urg6div7fE1BF8Zn93lLk5zgSHLuzFds15e7OaU#_4", "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "Selventa" } ] }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAgC_0urg6div7fE1BF8Zn93lLk5zgSHLuzFds15e7OaU#assertion", "http://www.w3.org/ns/prov#hadPrimarySource" : [ { "@id" : "http://www.ncbi.nlm.nih.gov/pubmed/14718385" } ], "http://www.w3.org/ns/prov#wasDerivedFrom" : [ { "@id" : "http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel" }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAgC_0urg6div7fE1BF8Zn93lLk5zgSHLuzFds15e7OaU#_3" } ] } ], "@id" : "http://www.tkuhn.ch/bel2nanopub/RAgC_0urg6div7fE1BF8Zn93lLk5zgSHLuzFds15e7OaU#provenance" }, { "@graph" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAgC_0urg6div7fE1BF8Zn93lLk5zgSHLuzFds15e7OaU", "http://purl.org/dc/terms/created" : [ { "@type" : "http://www.w3.org/2001/XMLSchema#dateTime", "@value" : "2014-07-03T14:30:19.755+02:00" } ], "http://purl.org/pav/createdBy" : [ { "@id" : "http://orcid.org/0000-0001-6818-334X" }, { "@id" : "http://orcid.org/0000-0002-1267-0234" } ] } ], "@id" : "http://www.tkuhn.ch/bel2nanopub/RAgC_0urg6div7fE1BF8Zn93lLk5zgSHLuzFds15e7OaU#pubinfo" } ]