sub:provenance {
beldoc: dce:description "Approximately 61,000 statements." ;
dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title "BEL Framework Large Corpus Document" ;
pav:authoredBy sub:_6 ;
pav:version "1.4" .
sub:_4 dce:identifier "OMIM summary: Human: MEF2A" ;
dce:title "OMIM summary: Human: MEF2A" ;
dce:type "Online Resource" .
sub:_5 prov:value "% OMIM summary: Human: The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD ({159970}), myogenin ({159980}), MYF5 ({159990}), and MRF4 ({159991}) are 1 class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous ' and 'deficiens ' and the human serum response factor SRF ({600589})), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain." ;
prov:wasQuotedFrom sub:_4 .
sub:_6 rdfs:label "Selventa" .
sub:assertion prov:hadPrimarySource sub:_4 ;
prov:wasDerivedFrom beldoc: ,
sub:_5 .
}