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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAgWP1uf_fduEqs7_NrDSVkwjkDGTAYrU6rKX3F_-kgZw#_4 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAgWP1uf_fduEqs7_NrDSVkwjkDGTAYrU6rKX3F_-kgZw#_3 http://www.w3.org/ns/prov#value The Wnt/Ca(2+)/cGMP pathway mediated by Frizzled-2 was discovered recently. Activation of this pathway leads to increased intracellular concentrations of Ca(2+) and decreased intracellular concentrations of cGMP. On the basis of results from these three analyses, the cGMP-specific phosphodiesterase, PDE6, is demonstrated to be an effector for the Wnt/Ca(2+)/cGMP signalling pathway of development, which is mediated by Frizzled-2. http://www.tkuhn.ch/bel2nanopub/RAgWP1uf_fduEqs7_NrDSVkwjkDGTAYrU6rKX3F_-kgZw#_3 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/15494017 http://www.tkuhn.ch/bel2nanopub/RAgWP1uf_fduEqs7_NrDSVkwjkDGTAYrU6rKX3F_-kgZw#_4 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAgWP1uf_fduEqs7_NrDSVkwjkDGTAYrU6rKX3F_-kgZw#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/15494017 http://www.tkuhn.ch/bel2nanopub/RAgWP1uf_fduEqs7_NrDSVkwjkDGTAYrU6rKX3F_-kgZw#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAgWP1uf_fduEqs7_NrDSVkwjkDGTAYrU6rKX3F_-kgZw#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAgWP1uf_fduEqs7_NrDSVkwjkDGTAYrU6rKX3F_-kgZw#_3 http://www.tkuhn.ch/bel2nanopub/RAgWP1uf_fduEqs7_NrDSVkwjkDGTAYrU6rKX3F_-kgZw#pubinfo http://www.tkuhn.ch/bel2nanopub/RAgWP1uf_fduEqs7_NrDSVkwjkDGTAYrU6rKX3F_-kgZw http://purl.org/dc/terms/created 2014-07-03T14:30:28.839+02:00 http://www.tkuhn.ch/bel2nanopub/RAgWP1uf_fduEqs7_NrDSVkwjkDGTAYrU6rKX3F_-kgZw http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAgWP1uf_fduEqs7_NrDSVkwjkDGTAYrU6rKX3F_-kgZw http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234