sub:provenance { beldoc:dce:description "Approximately 2000 hand curated statements drawn from 57 PubMeds." ; dce:rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved." ; dce:title "BEL Framework Small Corpus Document" ; dc:license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" ; pav:authoredBysub:_5 ; pav:version "1.6" . sub:_4prov:value """Here we tested how expression of COUP–TFI affected TCDD activity from the natural ERE sequences from the pS2 and c-fos promoters in transiently transfected MCF-7 cells. E2 alone stimulated a 1.6- to 2.1-fold induction in luciferase activity from the pS2 ERE (Fig. 8A). 4-OHT blocked the E2 activity, indicating the specificity of the induction by ER. TCDD alone gave a 1.4-fold induction in luciferase activity. Cotreatment with TCDD suppressed E2-stimulated luciferase activity. COUP–TFI inhibited both E2- and TCDD-stimulated luciferase activity from pS2.""" ; prov:wasQuotedFrompubmed:10620335 . sub:_5rdfs:comment "support@belframework.org" ; rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:10620335 ; prov:wasDerivedFrombeldoc: , sub:_4 . }