. . . . . . . . . . . . . "a(SCHEM:\"serum insulin\") -> tscript(p(MGI:Srebf1))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "SCD and D6D/D5D, these desaturases share common regulatory freatures, including dependence of expression on insulin, suppression by highly unsaturated fatty acids, and induction by peroxisome proliferators. A key regulator of desaturase gene expression is sterol-regulatory element binding protein-1c (SREBP-1c) which mediates transcriptional activation of the SCD and D6D genes by insulin and inhibition by highly unsaturated fatty acids. % Highly unsaturated fatty acids decrease stability of SREBP-1 mRNA...SREBP-1c activates the transcription of SCD-1, D6D and probably D5D genes." . . "Selventa" . . . . "2014-07-03T14:30:07.311+02:00"^^ . . .