. . . . . . . . . . . . . . "act(p(HGNC:BCL2L1)) -| bp(MESHPP:Apoptosis)" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "We report here that the phosphorylation of BAD at Ser-155 within the BH3 domain is a second phosphorylation-dependant mechanism that inhibits the death promoting activity of BAD. Phosphorylation at Ser-155, similar to phosphorylation at SER-112 and Ser-136, inhibits BAD-induced death-promoting activity but does so in a different manner. Phosphorylation at Ser-155 does not induce 14-3-3 binding and ctoplasmic sequestration but instead directly blocks BH3-dependent dimerization with Bcl-XL. The binding of Bcl-XL by the BH3 domain may cause Bcl-XL to release APAF-1 or regulate other Bcl-XL activites resulting in a caspase 9-initiated cascade of proteolysis and induction of apoptosis." . . "Selventa" . . . . "2014-07-03T14:29:51.220+02:00"^^ . . .